Testosterone Boosters vs Creatine | Which One Is Better?

Decisions. Decisions. Decisions. It’s what life is all about. And unfortunately for you, there’s no escaping making difficult choices even when you are contemplating a solution for your aspirations around muscle growth, athleticism and healthy testosterone levels. So next is yet another X versus Y analysis. Testosterone boosters and creatine are on the chopping block this time. I will help you make sense of both. That way, you can figure out which is the right path for you using proven, reliable information.

Quick summary

  • Testosterone boosters primarily boost free testosterone while creatine primarily supports muscle growth.
  • Both testosterone boosters and creatine have minimal side effects.
  • If you are young and don’t have problems with low testosterone, don’t do T-boosters.

What are testosterone boosters?

Testosterone boosters (or T-boosters) are design to, well, boost testosterone. But it’s not that simple. Testosterone boosters do not introduce the hormone directly into your bloodstream. Instead, they stimulate your body’s own production. In this sense, they differ from testosterone replacement therapy (TRT).

It would probably be more accurate to refer to testosterone boosters as testosterone production boosters. But what do I know? In the market, you are more likely to come across these products categorized as testosterone supplements or testosterone boosters. Testosterone boosters are typically made from plant extracts, amino acids, minerals and/or vitamins.

What is creatine?

Creatine is a fitness supplement made from the amino acids glycine, l-arginine and l-methionine. It is hailed for accelerating muscle gain and athletic performance. That’s why it is most widely used by pro athletes, bodybuilders and fitness enthusiasts. Unlike testosterone boosters which are lab engineered, the body actually creates its own creatine via the kidneys and liver. You can also get it through everyday meals such as seafood and red meat. It is stored in muscle and brain cells as phosphocreatine (or creatine phosphate). Phosphocreatine produces ATP (adenosine triphosphate), a source of quick energy for the cells.

Are there any similarities in their benefits? 

While their primary goals are not the same, testosterone boosters do have some similarities in their benefits. It is important to note that in listing similarities between T-boosters and creatine, these do not necessarily apply to all T-boosters. Remember, testosterone boosters do not have ingredient uniformity. They are not even identical in the number of distinct ingredients. Some have just three or four ingredients while others have more than a dozen. So I will base this comparison on the core benefits of a T-booster.


  • Both supplement types support muscle development, physical performance, physical strength and fat loss. Creatine promotes leaner and more muscular physique.
  • Both reduce or slow the onset of fatigue.
  • Both improve cognitive function though I would say creatine does so to a significantly greater extent than T-boosters. Creatine enhances cognitive function including memory and intelligence.

Unique Benefits

Testosterone Boosters

  • Increase natural production of free testosterone by the body.
  • Potential to directly impact muscle growth and strength gains through their influence on hormonal levels.
  • Improve mood, reduce irritability and lower stress.
  • Enhance sex drive, sperm count and sperm health.


Side effects to watch out for

Testosterone boosters

As far as a solution for low testosterone that has minimal side effects goes, testosterone boosters are arguably the best you can get. That is, apart from regular exercise, sufficient sleep and changes in diet. I’m not saying testosterone boosters have zero side effects though. 

For starters, you cannot make such a blanket statement for such a vast industry with hundreds of distinct products. What I can say is that given testosterone booster formulation comprises plant extracts, minerals, vitamins and amino acids, the likelihood of adverse reaction is low. That said, t-boosters may cause dizziness, nausea, vomiting and/or stomach upset. Check with your doctor though as some medical conditions and medication may not be compatible with testosterone boosters.


Creatine is made from amino acids. Better yet, the body makes its own creatine so the supplement is only meant to complement existing supply. Like testosterone boosters therefore, the likelihood of side effects is low. Perhaps even lower because you have a small, fixed set of natural ingredients. Some people may experience nausea, stomach discomfort, cramps and/or diarrhea. Like with testosterone boosters though, check in with your doctor if you have been diagnosed with a long term illness or are on long term prescription drugs. People with diabetes, kidney and liver problems should tread especially cautiously.

Final Thoughts

Time to make a choice. First rule, if it works don’t fix it. I would advise that if you are young and don’t have problems with low testosterone, don’t do T-boosters. At all. If that’s the case and you want a supplement that supports your fitness or athletics goals, go for creatine instead. T-boosters like TestoPrime are better suited for middle-aged and older men who already grapple with low testosterone almost by default so want a supplement that improves their free testosterone levels while supporting their muscle and strength building objectives.

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About the Author

Sam is a passionate health and fitness enthusiast who has been interested in supplements, fitness, and wellness for over 10 years. He is the founder of Great Green Wall - the health and wellness brand and has completed multiple fitness certificates, including personal training and nutrition certifications. Sam has been working as a personal trainer for the past three years and is dedicated to helping his clients achieve their fitness goals and lead healthier lifestyles. He believes that a healthy lifestyle is crucial to a happy and fulfilling life and is committed to sharing his knowledge and passion with others.

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